Performance measure | Placebo | Cannabis | Effect | ||||
---|---|---|---|---|---|---|---|
Day 1 | Day 3 | Day 1 | Day 3 | ||||
Perceived deficits, PDQ score, mean (95% CI)* | 19.97 (16.12 to 24.86) | 19.13 (14.73 to 24.39) | 20.33 (15.73 to 26.08) | 21.20 (17.47 to 26.33) | 1.70 (−3.23 to 6.07) | ||
Fatigue, mFIS score, mean (95% CI)† | 32.83 (26.50 to 38.78) | 35.00 (28.90 to 39.87) | 34.27 (27.50 to 39.67) | 34.63 (28.99 to 40.36) | −1.80 (−8.29 to 3.56) | ||
Symptoms, BSI score, mean (95% CI)‡ | 17.43 (12.57 to 22.06) | 9.43 (7.01 to 11.97) | 19.13 (12.73 to 26.29) | 14.00 (8.80 to 20.86) | 2.87 (−4.58 to 9.63) | ||
Performance measure | Placebo | Cannabis | Effect | ||||
Day 1 | Day 2 | Day 3 | Day 1 | Day 2 | Day 3 | ||
Perceived “highness,” SRHS–R score, mean (95% CI)§ | 1.03 (0.53 to 1.70) | 1.30 (0.70 to 2.03) | 1.83 (1.03 to 2.80) | 6.17 (5.09 to 7.13) | 6.63 (5.09 to 7.13) | 6.50 (5.47 to 7.27) | 5.04 (4.04 to 5.97) |
Note: BSI = brief symptom inventory, CI = confidence interval, mFIS = modified fatigue impact scale, PDQ = perceived deficits questionnaire, SRHS–R = subjective ratings of high and sedation – revised.
↵* Scores range from 0 to 80, with higher scores suggesting cognitive defects having a greater impact on quality of life.
↵† Scores range from 0 to 84, with higher scores suggesting greater fatigue affecting quality of life.
↵‡ Scores range from 0 to 208, with higher scores suggesting a greater number of problems/complaints and/or higher levels of distress resulting from those problems/complaints.
↵§ Scores range from 0 to 10, with higher scores suggesting a greater feeling of “high.”