RT Journal Article SR Electronic T1 An approach to the management of unintentional weight loss in elderly people JF Canadian Medical Association Journal JO CMAJ FD Canadian Medical Association SP 773 OP 780 DO 10.1503/cmaj.1031527 VO 172 IS 6 A1 Shabbir M.H. Alibhai A1 Carol Greenwood A1 Hélène Payette YR 2005 UL http://www.cmaj.ca/content/172/6/773.abstract AB UNINTENTIONAL WEIGHT LOSS, or the involuntary decline in total body weight over time, is common among elderly people who live at home. Weight loss in elderly people can have a deleterious effect on the ability to function and on quality of life and is associated with an increase in mortality over a 12-month period. A variety of physical, psychological and social conditions, along with age-related changes, can lead to weight loss, but there may be no identifiable cause in up to one-quarter of patients. We review the incidence and prevalence of weight loss in elderly patients, its impact on morbidity and mortality, the common causes of unintentional weight loss and a clinical approach to diagnosis. Screening tools to detect malnutrition are highlighted, and nonpharmacologic and pharmacologic strategies to minimize or reverse weight loss in older adults are discussed.