PT - JOURNAL ARTICLE AU - A. Humar AU - S. Sharma AU - D. Zoutman AU - K. C. Kain TI - Fatal falciparum malaria in Canadian travellers DP - 1997 Apr 15 TA - Canadian Medical Association Journal PG - 1165--1167 VI - 156 IP - 8 4099 - http://www.cmaj.ca/content/156/8/1165.short 4100 - http://www.cmaj.ca/content/156/8/1165.full SO - CMAJ1997 Apr 15; 156 AB - The authors report 2 cases of severe falciparum malaria in Canadians that had fatal outcomes. In the first case a man presented to a local hospital shortly after returning from Africa, but a diagnosis of malaria was not considered. He was transferred to a secondary and then to a tertiary care facility, where he subsequently died. Intravenous quinidine therapy, the treatment of choice, was unavailable at all 3 hospitals. In the second case, a woman taking chloroquine prophylaxis while visiting Nigeria developed cerebral malaria and died. These cases illustrate critical management issues: appropriate advice on malaria prevention before departure; consideration of malaria in all febrile people returning from an endemic area; ready access to parenteral therapy for severe malaria in Canadian hospitals; and an increase in awareness of travel medicine among family physicians.