PT  - JOURNAL ARTICLE
AU  - Habal, F. M.
AU  - Soldin, S. J.
AU  - Greenberg, G. R.
TI  - Cimetidine-resistant Zollinger-Ellison syndrome: successful management with ranitidine
DP  - 1983 Aug 01
TA  - Canadian Medical Association Journal
PG  - 256--258
VI  - 129
IP  - 3
4099  - http://www.cmaj.ca/content/129/3/256.short
4100  - http://www.cmaj.ca/content/129/3/256.full
SO  - CMAJ1983 Aug 01; 129
AB  - In a patient with the Zollinger-Ellison syndrome who had undergone vagotomy, pyloroplasty and, later, gastrojejunostomy, epigastric pain and stomal ulceration recurred despite the use of high doses (2700 mg/d) of cimetidine. Ranitidine, a new histamine H2-receptor antagonist, reversed all symptoms and healed the stomal ulcer without side effects, thus obviating the need for further surgery. Ranitidine may prove to be the drug of choice in the medical management of patients with the Zollinger-Ellison syndrome.