TY - JOUR T1 - Cytogenetic findings in over 2000 amniocenteses JF - Canadian Medical Association Journal JO - CMAJ SP - 846 LP - 850 VL - 129 IS - 8 AU - J. E. Allanson AU - B. C. McGillivray AU - J. G. Hall AU - D. Shaw AU - D. K. Kalousek Y1 - 1983/10/15 UR - http://www.cmaj.ca/content/129/8/846.abstract N2 - Between 1971 and 1981, 58 (2.8%) of 2037 amniocenteses performed in Vancouver revealed chromosome abnormalities, 25 of which were trisomy 21. Of the 58 referrals that yielded abnormalities, 37 (63.8%) were for a maternal age of 38 years or more. The rates of detection of such abnormalities for single-year intervals of maternal age beyond 35 years were comparable to those calculated from pooled data obtained in multicentre studies in the United States, Canada and Europe. ER -