@article {Dean297, author = {H. J. Dean and H. G. Friesen}, title = {Growth hormone therapy in Canada: end of one era and beginning of another}, volume = {135}, number = {4}, pages = {297--301}, year = {1986}, publisher = {CMAJ}, abstract = {This paper reviews the difficulties in diagnosing a true deficiency of growth hormone (GH), the long-term results of therapy, the Canadian experience in treating GH deficiency, including the contributions made by the Medical Research Council{\textquoteright}s Therapeutic Trial of Human Growth Hormone, and the occurrence of Creutzfeldt-Jakob disease in recipients of GH therapy. It also speculates on potential alternatives to treatment with GH derived from human pituitaries.}, issn = {0820-3946}, URL = {https://www.cmaj.ca/content/135/4/297}, eprint = {https://www.cmaj.ca/content}, journal = {CMAJ} }