Celiac disease | Abdominal pain, steatorrhea, flatulence, weight loss |
Primary eosinophilic gastroenteritis | Nausea, vomiting, diarrhea, dyspepsia, weight loss; uncommonly, obstructive-type symptoms (e.g., pyloric stenosis, intestinal obstruction) or ascites |
Eosinophilic granulomatosis with polyangiitis | Pulmonary symptoms most common, with asthma as the cardinal feature (> 90% of patients). Fatigue, weight loss, fever, arthralgias, rhinosinusitis, urinary abnormalities (e.g., hematuria, proteinuria) with or without renal dysfunction, neurologic dysfunction, purpura |
Carcinoid (neuroendocrine) tumour | Carcinoid syndrome, which may involve facial flushing, wheezing, diarrhea, abdominal cramping or peripheral edema; advanced small bowel disease may present with obstruction or ascites |
Drug-induced eosinophilia | Ranges from asymptomatic to life threatening; uncommonly, drug reaction with eosinophilia and systemic symptoms, including triad of skin eruption, fever and organ involvement (kidneys, heart, liver, lung). |