1 | Erythema migrans |
Large, red lesion with central clearing (“target lesion”) at the site of the initial tick bite May be accompanied by fever, headache and joint pain
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2 | Neurologic Lyme disease (neuroborrelosis) |
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| Cardiovascular Lyme disease |
Heart block Myocarditis Pericarditis
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3 | Arthritis |
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| Late neurological Lyme disease |
Encephalopathy Encephalitis Peripheral neuropathy
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| Acrodermatitis chronica atrophicans |
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| Post–Lyme disease syndrome |
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