Practice
HIV pre-exposure prophylaxis
Malika Sharma and Darrell H.S. Tan
CMAJ October 21, 2014 186 (15) E588; DOI: https://doi.org/10.1503/cmaj.140127
Malika Sharma
Division of Infectious Diseases (Sharma, Tan), University of Toronto; Faculty of Medicine (Tan), University of Toronto; Hassle Free Clinic (Tan), Toronto; Division of Infectious Diseases (Tan), St. Michael’s Hospital, Toronto, Ont.
MDDarrell H.S. Tan
Division of Infectious Diseases (Sharma, Tan), University of Toronto; Faculty of Medicine (Tan), University of Toronto; Hassle Free Clinic (Tan), Toronto; Division of Infectious Diseases (Tan), St. Michael’s Hospital, Toronto, Ont.
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HIV pre-exposure prophylaxis
Malika Sharma, Darrell H.S. Tan
CMAJ Oct 2014, 186 (15) E588; DOI: 10.1503/cmaj.140127
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- HIV pre-exposure prophylaxis (PrEP) is the regular use of antiretroviral medication by HIV-negative individuals to prevent HIV infection
- PrEP is efficacious in the prevention of HIV, with adherence being the critical determinant of effectiveness
- PrEP does not protect against other sexually transmitted infections
- PrEP is well-tolerated, with minimal short-term nausea
- The development of HIV resistance is a rare but real concern
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