We respectfully object to the interpretation1 of our commentary2 as one that would promote withholding information from screening participants. We essentially sought to express concerns about the proposed guideline because it entailed serious limitations, on multiple levels, best described by the authors themselves as follows:
The process of making these recommendations was challenging, often with opposing views in the panel. Particular challenges were the lack of randomised trials for colonoscopy and FIT [fecal immunochemical test] (which made us rely on modelled estimates of low certainty for screening benefit) and the uncertainty in people’s values and preferences.3
We stand by our assertion that this guideline project lacks the credibility to justify a drastic change in the philosophy of colorectal cancer screening in the face of robust evidence for the efficacy of organized screening.
Footnotes
Competing interests: Catherine Dubé is contracted by Ontario Health (Cancer Care Ontario) for the role of clinical lead for the ColonCancerCheck program, Ontario’s colorectal cancer screening program. No other competing interests were declared.