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Description and evaluation of an acute stroke unit

Stephen J. Phillips^*, Gail A. Eskes^*, Gordon J. Gubitz^* and on Elizabeth, II

From *the Division of Neurology, Department of Medicine, and the Department of Psychology, Dalhousie University and Queen Elizabeth II Health Sciences Centre, Halifax, NSPast and present members of the Queen Elizabeth II Health Sciences Centre Acute Stroke Team: Eslier Aguilar, Lindi Barkhouse, Joanne Brown-Bonomo, Krista Buchanan, Allison Callaghan, Cathy Ann Casault, Christine Christian, Wilma Clancy, Leanne Coleman-Kamphuis, Margie Collins, Mary-Elizabeth Cooper, Caroline Corkum, Penny Dalgarno, Sultan Darvesh, Jill Dollimount, Vicky Dwyer, Angela Edwards, Jill Flynn, Ann Grantmyre, Wendy Green, Ed Harrison, Janey Hughes, Judith Jarrett, Michelle MacKay, Clarke MacKenzie, Eileen MacKinnon, Abbigail May, Deidre McLean, Susan McNeil, Maureen Merchant, Shannon Nearing, Yvette Reidy, Steve Sampson, Shirley Sanford, Stancy Singh, Sandy Singleton, Susan Smith, Myrna Sutherland, Anne Wagner, Elan Wojick and the nursing staff of the Acute Stroke Unit

Correspondence to: Dr. Stephen J. Phillips, Division of Neurology, Rm. 3831, Halifax Infirmary, 1796 Summer St., Halifax NS B3H 3A7; fax 902 473-4438; stephill{at}is.dal.ca

Abstract

CLINICAL TRIALS HAVE DEMONSTRATED THE SUPERIORITY OF COORDINATED interdisciplinary stroke unit care over conventional treatment of stroke patients on general medical wards. The evidence is so strong that several national bodies have recommended that stroke unit care be widely implemented. Translation of these research findings and care guidelines into clinical practice, however, represents a challenge for health care systems unaccustomed to managing stroke in a coordinated manner. This report describes the organization, operation and outcomes of the Acute Stroke Unit at the Queen Elizabeth II Health Sciences Centre in Halifax. By replicating and adapting the core characteristics identified in the randomized trials, we have been able to demonstrate the effectiveness of stroke unit care in a routine clinical setting. Our experience may help facilitate the development of organized stroke care in Canada.

Despite this evidence, organized stroke unit care is not widely available in Canada,⁸ probably because of logistical barriers. For example, in a 1998 survey of acute care hospitals in Ontario, only 4% had a dedicated stroke unit.⁹ The purpose of this paper is to describe how the Acute Stroke Unit at the Queen Elizabeth II Health Sciences Centre (QEII) in Halifax has been able to provide effective care through replication and adaptation of the core characteristics identified in randomized trials.

Program description

The objective of our Acute Stroke Program is to provide optimal care for stroke patients and their families using an interdisciplinary approach to assessment, treatment, education and research. The program model, goals and anticipated long-term effects are outlined in Fig. 1.

View larger version (47K): [in this window] [in a new window]   Fig. 1: Model of Acute Stroke Unit, illustrating connection between daily activities of interdisciplinary team and their long-term effects. PULSES = Physical condition, Upper limb functions, Lower limb functions, Sensory components (including communication), Excretory functions, Support factors;10 UTI = urinary tract infection; DVT = deep vein thrombosis; PE = pulmonary embolism.

The QEII is a 1073-bed teaching hospital in Halifax that provides primary and secondary care for about 300 000 people and tertiary care for about an additional 500 000. The Division of Neurology offers a 24-hour consultation service to the QEII Emergency Department. In general, patients who present with uncomplicated transient ischemic attacks (TIAs) or non-disabling strokes are not admitted to hospital. The Neurosurgery Service usually manages patients with subarachnoid hemorrhage. All other patients with suspected or confirmed acute stroke (including patients with intracranial hemorrhage not requiring surgery) are admitted to the Acute Stroke Unit. Patients receiving thrombolytic therapy^11,12 are admitted to the intensive care unit and are transferred to the stroke unit after 24 hours. On any given day, the average number of patients in the Acute Stroke Unit is 17 (range 9–25). This includes patients in the acute phase of their illness, those receiving early rehabilitation, those awaiting transfer to an alternative level of care and those receiving palliative care.

The Acute Stroke Unit is located on an acute neurology ward that also houses a general neurology service managing patients with acute nonvascular neurological disorders. Different neurologists supervise the 2 services.

The composition and roles of our interdisciplinary stroke team are shown in Table 1. Other stroke units have reported similar staffing levels.¹³ Some team members also provide care for patients in the general neurology service. The nursing staff comprises 75% registered nurses (25% with national neuroscience certification or a post-RN course in neuroscience nursing) and 25% licensed practical nurses. Nurses function as active members of the interdisciplinary team, facilitating a patient-focused model of care delivery. The patient-to-nurse ratio is usually 4:1 during the day and 7:1 at night. Individual team members are responsible to their department heads for meeting standards of care delivery. The team coordinator reports to the manager of the Neurology Nursing Unit. The attending stroke neurologist reports to the head of the Division of Neurology.

The physician who assesses the patient upon admission records the clinical findings on a standardized history and physical form adapted from the Royal College of Physicians stroke audit package.¹⁴ This form minimizes the amount of writing required and prompts the physician to consider the salient features of the clinical assessment. The use of such a form improves the recording of information¹⁵ and, in our experience, makes information more accessible to the stroke team.

A standardized admission orders form prompts the physician to consider all aspects of care and to select an appropriate course of action from a menu of options. For patients assessed within the first 3 hours after ischemic stroke, an eligibility checklist and standing orders form facilitate thrombolysis treatment.

By completing a single requisition, the physician can initiate interdisciplinary assessment and treatment by the team's dietitian, neuropsychologist, occupational therapist, physiotherapist, social worker and speech-language pathologist (Table 1). Pharmacy support is provided routinely. Pastoral care services are also available. Other disciplines such as physical medicine and rehabilitation, neurosurgery, psychiatry and clinical psychology are consulted as needed. The team meets twice weekly to discuss the status of each patient and to update the plan of care.

We maintain a prospective computerized registry of all cases of stroke and TIA admitted to the Acute Stroke Unit. Data summarizing demographic details, stroke type, lesion localization, stroke severity, functional status, complications, investigations and other information are recorded during the hospital stay by the team coordinator. At discharge the data collection form is removed from the patient's chart by a research assistant who checks the accuracy of the information and enters it into the database. The registry is a useful clinical tool for program planning, research and quality assurance and audit purposes.

The stroke team has developed educational materials for patients and families to complement those published by organizations such as the Heart and Stroke Foundation. In-service training sessions concerning various aspects of the care of stroke patients are held regularly. For the past several years we have organized annual workshops attended by health care professionals from the Maritime provinces. Revenues from the workshops are used to support the professional education of team members. Trainees from the various team disciplines rotate through the program.

We have participated in several clinical trials^{16,17,18,19,20,21} and have used our registry for original projects^{22,23,24,25,26} as well as for quality control and audit purposes. Our research is clinically oriented, focusing on treatment and outcomes. Our philosophy is to integrate patient care and research as much as possible. Research personnel contribute to the clinical, educational and administrative activities of the team, and team members participate in research projects.

Administration meetings are held every 2 to 4 weeks and provide team members with an equal opportunity to participate in the decision-making related to the functioning of the program. An annual 1-day retreat provides a forum for in-depth review of the program (including the registry data) and allows for strategic planning.

The administration and funding of the component parts of the are organized on a departmental basis. Research contracts and grants support our research personnel and registry. An economic analysis using data from the Stroke Unit Trialists' Collaboration indicated that stroke units are unlikely to consume extra resources and may even release some for use elsewhere.²⁷

Preliminary evaluation

Table 2 provides a summary description of the patients admitted to the Acute Stroke Unit between Jan. 1, 1997, and Dec. 31, 2000. During this time the in-hospital case-fatality rate was 13% (95% confidence interval [CI] 11%–15%). Table 3 summarizes stroke survivors' recovery of function and minimization of disability (as measured by change in Barthel Index scores^10,32 between admission and discharge), length of stay in the Acute Stroke Unit and the proportion of patients discharged home.

We evaluated patient satisfaction by questionnaire during the autumn of 1999. The questions were constructed to obtain feedback related to program goals. The questionnaire was given to 34 consecutive patients just before discharge from the stroke unit. If required, a member of the family or the QEII volunteer service assisted in completing the questionnaire. Thirty-two patients (94%) returned the questionnaire. On a scale of 1 (very dissatisfied) to 5 (very satisfied), the mean rating for items related to care delivery was 4.6.

Length of stay, complications, and death or need for long-term institutional care for patients admitted to the Acute Stroke Unit were compared with these outcomes for TIA and stroke patients admitted during 1993–1996, before the stroke unit was established (Table 4). Despite the methodological limitations of a before–after comparison, the data show that patients managed in the stroke unit had a shorter median length of stay than those managed beforehand. With a cost of $1066 per day at the QEII, a 2-day reduction in median length of stay per stroke unit patient translates into a saving of more than $2.1 million per 1000 patients treated.

In the Acute Stroke Unit the odds of symptomatic deep vein thrombosis occurring were reduced by 68% (95% CI 16%–89%) (Table 4). The odds of death or needing long-term institutional care after a median follow-up of 10 days was reduced by 3% (n = 943; 95% CI 19% reduction to 16% increase, p = 0.12). This trend is in keeping with the results of the meta-analysis of randomized trials (n = 3812), which showed an odds reduction of 23% (95% CI 12%–32%, p < 0.001) after a median follow-up of 1 year.¹

Comments

The Acute Stroke Program at the QEII integrates clinical care, education and research to maintain a high standard of care and education for patients and families, while developing the knowledge and various interests of the disciplines contributing to the program. Patients report a high level of satisfaction with the care they receive. The before–after analysis indicated that stroke unit care at our hospital has been associated with a statistically and economically significant reduction in length of stay and a reduction in the incidence of deep vein thrombosis. The program provides an ideal training environment for health care professionals from a broad range of disciplines. An organized approach also facilitates clinical research, including participation in treatment trials.

Areas needing growth and development include our neurovascular ambulatory care program and training in stroke medicine for postgraduate medical trainees. Also, in our aspirations for smooth and continuous patient care, we would like to improve the transition between acute stroke care and long-term rehabilitation, and between hospital care and community living.

Recommendations for stroke-unit care have been published in Europe,³³ the United States³⁴ and Canada.³⁵ We hope that this description of our experience helps facilitate the development of a more organized approach to stroke care in Canada.

ß See related article page 649

Footnotes

The clinical care forms described in the text are available from the corresponding author upon request.

This article has been peer reviewed.

Contributors: Stephen Phillips, Gordon Gubitz, and Gail Eskes have all made major contributions to the development and operation of the Acute Stroke Unit at Queen Elizabeth II Health Sciences Centre. Dr. Eskes provided the impetus to report our experience. Dr. Phillips wrote the first draft of the manuscript. Drs. Gubitz and Eskes provided essential input into the analyses of our registry database, and into all revisions of the manuscript. All three authors gave final approval of the version submitted for publication.

Acknowledgements: The Acute Stroke Unit registry has been supported by funds from the Heart and Stroke Foundation of Nova Scotia, GlaxoSmithkline Inc., AstraZeneca Canada Inc., Leo Pharma Inc., Bayer Health Care Division, Sanofi Canada Inc., Hoffmann–La Roche Ltd., Aventis Pharma Inc. and Servier Canada Inc.

Competing interests: None declared.

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