CMAJ • June 17, 2008; 178 (13). doi:10.1503/cmaj.070734.
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A 1-week-old newborn with hypercalcemia and palpable nodules: subcutaneous fat necrosis

Fahed Aljaser, MD and Michael Weinstein, MD

Division of Pediatric Medicine, Hospital for Sick Children and University of Toronto, Toronto, Ont.


Figure 113
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  		Figure 1: A 5-day-old infant with lesions of subcutaneous fat necrosis. The largest mass (black arrow) measured 2 x 2.5 cm. Two smaller lesions (white arrows) were located in the left posterior axillary area.

 

Figure 213
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  		Figure 2: Left: A typical photomicrograph from a different patient showing lobular panniculitis with sparing of the dermis and epidermis (original magnification x 20). Right: A high-power view shows that the inflammatory infiltrate is mixed and composed of histiocytes, lymphocytes, neutrophils and eosinophils. Cleft-like spaces (arrow) suggestive of dissolved crystals can be seen at the periphery of some of the fat cysts (original magnification x 400). Reproduced with permission from Macmillan Publishers Ltd: Journal of Perinatology (Diamantis et al.2) © 2006.