CMAJ • March 27, 2007; 176 (7). doi:10.1503/cmaj.060607.
© 2007 Canadian Medical Association or its licensors
All editorial matter in CMAJ represents the opinions of the authors and not necessarily those of the Canadian Medical Association.
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Suitability of recommended limits for fasting glucose tests in women with polycystic ovary syndrome

Claudia Gagnon and Jean-Patrice Baillargeon

From the Department of Medicine, Division of Endocrinology, Université de Sherbrooke, Sherbrooke, Que.


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  		Table 1.

 

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  		Table 2.

 

Figure 117
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  		Fig. 1: A 2 x 2 table showing the performance characteristics of the 2-h glucose tolerance test (cutoff ≥ 7.8 mmol/L) compared with the fasting plasma glucose test (cutoff ≥ 5.6 mmol/L). PPV = positive predictive value, NPV = negative predictive value.

 

Figure 217
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  		Fig. 2: Receiver operating characteristic curve of the association between fasting plasma glucose and abnormal glucose tolerance. The area under the curve was 0.828 (95% confidence interval 0.735–0.921). The optimal cutoff for the test is the point closest to the upper-left corner of the graph, which corresponds to a fasting plasma glucose measurement of 5.0 mmol/L.

 

Figure 317
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  		Fig. 3: A logarithmic representation of the likelihood ratio of having abnormal glucose tolerance, as a function of fasting plasma glucose test results. At a glucose concentration of 4.4 mmol/L, the likelihood of finding that test result among patients with abnormal glucose tolerance is equal to its likelihood among those with normal glucose tolerance.