CMAJ • March 27, 2007; 176 (7). doi:10.1503/cmaj.061057.
© 2007 Canadian Medical Association or its licensors
All editorial matter in CMAJ represents the opinions of the authors and not necessarily those of the Canadian Medical Association.
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Right arrow Nephrology

Negative anion gap and elevated osmolar gap due to lithium overdose

Manish M. Sood and Robert Richardson

Department of Medicine, Division of Nephrology, Toronto General Hospital, University Health Network, Toronto, Ont.


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  		Table 1.

 

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  		Fig. 1: Inverse correlation between lithium level and anion gap over time. Of note, the initial anion gap of –2 mmol/L corresponded to a lithium level of 14.5 mmol/L.

 

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  		Fig. 2: Effects of intermittent hemodialysis and continuous venovenous hemodiafiltration on lithium levels. Time zero was arrival at our centre. Arrow indicates rebound in lithium levels that required initiation of continous venovenous hemodiafiltration.