CMAJ January 16, 2007; 176 (2).
First published December 19, 2006; doi:10.1503/cmaj.061020
© 2007 Canadian Medical Association or its licensors
All editorial matter in CMAJ represents the opinions of the authors and not necessarily those of the Canadian Medical Association.
The cost-effectiveness of drug-eluting stents: a systematic review
Suzanne Ligthart,
Floortje Vlemmix,
Nandini Dendukuri and
James M. Brophy
From the Department of Medical Technology Assessment (Ligthart, Vlemmix), University Medical Centre Nijmegen, Nijmegen, the Netherlands; the Technology Assessment Unit (Ligthart, Vlemmix, Dendukuri, Brophy), McGill University Health Centre, Montréal, Que.; and the Departments of Epidemiology and Biostatistics (Dendukuri, Brophy) and Medicine (Brophy), McGill University, Montréal, Que.

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Fig. 1: Results of literature search for cost-effectiveness analyses comparing drug-eluting stents (DES) and bare-metal stents (BMS). See Methods for search terms. INAHTA = International Network of Agencies for Health Technology Assessment (www.inahta.org).
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Fig. 2: Results of classification and regression tree (CART) analysis showing study characteristics that were predictive of the main outcome measure (study favoured use of drug-eluting stents). Percentages in parentheses indicate the proportion of studies that favoured widespread use. Quality = quality as determined with the use of the instrument in Appendix 1 (available online at www.cmaj.ca/cgi/content/full/176/2/199/DC1); sponsored = study directly sponsored by manufacturer of drug-eluting stent.
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