CMAJ • March 30, 2004; 170 (7). doi:10.1503/cmaj.1031185.
© 2004 Canadian Medical Association or its licensors
All editorial matter in CMAJ represents the opinions of the authors and not necessarily those of the Canadian Medical Association.
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Review
Synthèse

Current and future concepts in stroke prevention

Fintan O'Rourke, Naeem Dean, Naveed Akhtar and Ashfaq Shuaib

From the Stroke Prevention Clinic, University of Alberta Hospital, Mackenzie Health Sciences Centre (O'Rourke, Akhtar, Shuaib), and the Department of Medicine, Royal Alexandra Hospital (Dean), Edmonton, Alta.

Abstract

STROKE IS A MAJOR CAUSE OF MORBIDITY and mortality in an aging population. The current understanding of the pathophysiology of atherosclerotic diseases, the most common cause of stroke, and the evidence for existing therapeutic interventions for the prevention of stroke are presented. Specifically, we review the evidence for antiplatelet agents, anticoagulants, antihypertensive medications, lipid-lowering agents and carotid endarterectomy for stroke prevention.


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