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From the Departments of Medicine (Thompson, Gin), Surgery (Christenson, Innes, McKnight, Grafstein), Pathology and Laboratory Medicine (Rosenberg), and Health Care and Epidemiology (Anis, Wong, Singer), University of British Columbia, the Centre for Health Evaluation and Outcome Sciences (Christenson, Innes, Grafstein, Anis, Tilley), the Departments of Emergency Medicine (Christenson, Innes, Boychuk, Grafstein), Medicine (Thompson), and Pathology and Laboratory Medicine (Rosenberg), Providence Health Care, St. Paul's Hospital, and the Departments of Emergency Medicine (McKnight) and Medicine (Gin), Vancouver Hospital, Vancouver, BC
Background: Most Canadian emergency departments use an unstructured, individualized approach to patients with chest pain, without data to support the safety and efficiency of this practice. We sought to determine the proportions of patients with chest discomfort in emergency departments who either had acute coronary syndrome (ACS) and were inappropriately discharged from the emergency department or did not have ACS and were held for investigation.
Methods: Consecutive consenting patients aged 25 years or older presenting with chest discomfort to 2 urban tertiary care emergency departments between June 2000 and April 2001 were prospectively enrolled unless they had a terminal illness, an obvious traumatic cause, a radiographically identifiable cause, severe communication problems or no fixed address in British Columbia or they would not be available for follow-up by telephone. At 30 days we assigned predefined explicit outcome diagnoses: definite ACS (acute myocardial infarction [AMI] or definite unstable angina) or no ACS.
Results: Of 1819 patients, 241 (13.2%) were assigned a 30-day diagnosis of AMI and 157 (8.6%), definite unstable angina. Of these 398 patients, 21 (5.3%) were discharged from the emergency department without a diagnosis of ACS and without plans for further investigation. The clinical sensitivity for detecting ACS was 94.7% (95% confidence interval [CI] 92.5%– 96.9%) and the specificity 73.8% (95% CI 71.5%– 76.0%). Of the patients without ACS or an adverse event, 71.1% were admitted to hospital or held in the emergency department for more than 3 hours.
Interpretation: The current individualized approach to evaluation and disposition of patients with chest discomfort in 2 Canadian tertiary care emergency departments misses 5.3% of cases of ACS while consuming considerable health care resources for patients without coronary disease. Opportunities exist to improve both safety and efficiency.
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