Advertisement
ADVANCED SEARCH

This Article Full Text Full Text (PDF) Submit a response View responses Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Irving, J. A. Articles by Wadsworth, L. D. Search for Related Content PubMed PubMed Citation Articles by Irving, J. A. Articles by Wadsworth, L. D. Related Collections Drug misuse Hematologic pathology (including blood transfusion) Related Article

Element of caution: a case of reversible cytopenias associated with excessive zinc supplementation

From the Department of Pathology and Laboratory Medicine (Irving, Mattman, Lockitch, Wadsworth) and the Division of Pediatric Neurology (Farrell), Children's and Women's Health Centre of British Columbia and the University of British Columbia, Vancouver, BC.

Correspondence to: Dr. Louis D. Wadsworth, Program Head, Hematopathology, Department of Pathology and Laboratory Medicine, BC Children's Hospital, 4480 Oak St., Vancouver BC V6H 3V4; fax 604 875-2815; lwadsworth{at}cw.bc.ca

Abstract

ZINC IS A COMMON SUPPLEMENT AND IS WIDELY AVAILABLE as a standard component of many over-the-counter products. A number of reports have identified an association between excessive zinc intake and severe cytopenia. We report a case of zinc-induced copper deficiency in a young adult to illustrate this under-recognized cause of anemia and neutropenia.

This article has been cited by other articles:

				A.S. Haddad, V. Subbiah, A.E. Lichtin, K.S. Theil, and J.P. Maciejewski Hypocupremia and bone marrow failure Haematologica, January 1, 2008; 93(1): e1 - e5. [Abstract] [Full Text] [PDF]

				N. Kumar Copper Deficiency Myelopathy (Human Swayback) Mayo Clin. Proc., October 1, 2006; 81(10): 1371 - 1384. [Abstract] [Full Text] [PDF]

				J. Wang, Y. Song, L. Elsherif, Z. Song, G. Zhou, S. D. Prabhu, J. T. Saari, and L. Cai Cardiac Metallothionein Induction Plays the Major Role in the Prevention of Diabetic Cardiomyopathy by Zinc Supplementation Circulation, January 31, 2006; 113(4): 544 - 554. [Abstract] [Full Text] [PDF]

eLetters:

HOME	CURRENT ISSUE	PAST ISSUES	COLLECTIONS	HELP	SEARCH
Copyright 1995-2003, Canadian Medical Association. All rights reserved. ISSN 1488-2329 (e) 0820-3946 (p) All editorial matter in CMAJ represents the opinions of the authors and not necessarily those of the Canadian Medical Association.