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From *the MacKenzie Health Services Research Group and the Division of Rheumatology, Queen's University, Kingston, Ont.; the Canadian Multicentre Osteoporosis Study (CaMos) National Coordinating Centre and the CaMos Analysis Centre, McGill University, Montreal, Que.; ¶the Department of Epidemiology and Biostatistics, McGill University, Montreal, Que.; the Departments of Medicine at **Laval University, Sainte-Foy, Que., the University of Toronto, Toronto, Ont., McMaster University, Hamilton, Ont., and the University of Calgary, Calgary, Alta.; and ¶¶Eli Lilly Canada Inc., Toronto, Ont.***The list of CaMos investigators appears at the end of this article.Investigators in the Canadian Multicentre Osteoporosis Study Research Group:
McGill University, Montreal General Hospital, Montreal (coordinating centre): Alan Tenenhouse (principal investigator), Suzette Poliquin (national coordinator), Lawrence Joseph (study statistician), Lucie Blondeau (statistician), Claudie Berger (statistician), Suzanne Lefebvre (administrative assistant); University of British Columbia, Vancouver: Jerilynn C. Prior (centre director), Brian Lentle (Radiology Study consultant), Yvette Vigna (centre coordinator); University of Alberta, Edmonton: Stuart Jackson (medical physicist), Loralee Robertson (research assistant); University of Calgary: David A. Hanley (centre director), Jane Allan (centre coordinator); University of Saskatchewan, Saskatoon: Wojciech P. Olszynski (centre director), and Pat Krutzen and Jola Kedra (centre coordinators); McMaster University, Hamilton, Ont.: Jonathan D. Adachi (centre director), Laura Pickard (centre coordinator); University of Toronto: Nancy Kreiger (study epidemiologist), Timothy M. Murray (centre director), Barbara Gardner-Bray (centre coordinator); Queen's University, Kingston, Ont.: Tassos Anastassiades (centre director), and Pamela Hartman and Barbara Matthews (centre coordinators); Laval University, Sainte-Foy, Que.: Jacques P. Brown (centre director), and Nathalie Migneault-Roy and Evelyne Lejeune (centre coordinators); Dalhousie University, Halifax: Roger S. Rittmaster (centre director), Susan Kirkland (epidemiologist), Barbara Stanfield (centre coordinator); and Memorial University, St. John's: Carol Joyce (centre director), Minnie Parsons (centre coordinator)
Background: The Medical Outcomes Study 36-item Short Form (SF-36) is a widely used measure of health-related quality of life. Normative data are the key to determining whether a group or an individual scores above or below the average for their country, age or sex. Published norms for the SF-36 exist for other countries but have not been previously published for Canada.
Methods: The Canadian Multicentre Osteoporosis Study is a prospective cohort study involving 9423 randomly selected Canadian men and women aged 25 years or more living in the community. The sample was drawn within a 50-km radius of 9 Canadian cities, and the information collected included the SF-36 as a measure of health-related quality of life. This provided a unique opportunity to develop age- and sex-adjusted normative data for the Canadian population.
Results: Canadian men scored substantially higher than women on all 8 domains and the 2 summary component scales of the SF-36. Canadians scored higher than their US counterparts on all SF-36 domains and both summary component scales and scored higher than their UK counterparts on 4 domains, although many of the differences are not large.
Interpretation: The differences in the SF-36 scores between age groups, sexes and countries confirm that these Canadian norms are necessary for comparative purposes. The data will be useful for assessing the health status of the general population and of patient populations, and the effect of interventions on health-related quality of lif
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